Variations in genes regulating tumor-associated macrophages (TAMs) to predict outcomes of bevacizumab-based treatment in patients with metastatic colorectal cancer: results from TRIBE and FIRE3 trials

BACKGROUND: Tumor-associated macrophages (TAMs) with the M2-like phenotype are regulated by mainly NF-kB pathway including TBK1, which can influence tumor progression by secretion of proangiogenic factors such as vascular endothelial growth factor. The CCL2/CCR2 axis, histidine-rich glycoprotein (HR...

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Detalhes bibliográficos
Publicado no:Ann Oncol
Main Authors: Sunakawa, Y., Stintzing, S., Cao, S., Heinemann, V., Cremolini, C., Falcone, A., Yang, D., Zhang, W., Ning, Y., Stremitzer, S., Matsusaka, S., Yamauchi, S., Parekh, A., Okazaki, S., Berger, M. D., Graver, S., Mendez, A., Scherer, S. J., Loupakis, F., Lenz, H.-J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658546/
https://ncbi.nlm.nih.gov/pubmed/26416897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdv474
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