A genetic variant in Rassf1a predicts outcome in mCRC patients treated with cetuximab plus chemotherapy: results from FIRE-3 and JACCRO 05 and 06 trials

The Hippo pathway is involved in colorectal cancer (CRC) development and progression. The Hippo regulator Rassf1a is also involved in the Ras signaling cascade. In this work, we tested single nucleotide polymorphisms within Hippo components and their association with outcome in CRC patients treated...

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Detalhes bibliográficos
Publicado no:Pharmacogenomics J
Main Authors: Sebio, A., Stintzing, S., Heinemann, V., Sunakawa, Y., Zhang, W., Ichikawa, W., Tsuji, A., Takahashi, T., Parek, A., Yang, D., Cao, S., Ning, Y., Stremitzer, S., Matsusaka, S., Okazaki, S., Barzi, A., Berger, M., Lenz, H-J
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378677/
https://ncbi.nlm.nih.gov/pubmed/27698403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2016.69
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