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Investigating the Selectivity of Metalloenzyme Inhibitors in the Presence of Competing Metalloproteins
Metalloprotein inhibitors (MPi) are an important class of therapeutics for the treatment of a variety of diseases, including hypertension, cancer, and HIV/AIDS. However, despite their clinical success, there is an apprehension that MPi may be less selective than other small molecule therapeutics, an...
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| Vydáno v: | ChemMedChem |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4658394/ https://ncbi.nlm.nih.gov/pubmed/26412596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201500293 |
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