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Investigation of self-immolative linkers in the design of hydrogen peroxide activated metalloprotein inhibitors

A series of self-immolative boronic ester protected methyl salicylates and metal-binding groups with various linking strategies have been investigated for their use in the design of matrix metalloproteinase proinhibitors.

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Detalhes bibliográficos
Main Authors: Major Jourden, Jody L., Daniel, Kevin B., Cohen, Seth M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682828/
https://ncbi.nlm.nih.gov/pubmed/21677985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1cc12526e
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