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JTE-522-induced apoptosis in human gastric adenocarinoma cell line AGS cells by caspase activation accompanying cytochrome C release, membrane translocation of Bax and loss of mitochondrial membrane potential

AIM: To investigate the role of the mitochondrial pathway in JTE-522-induced apoptosis and to investigate the relationship between cytochrome C release, caspase activity and loss of mitochondrial membrane potential (△Ψm). METHODS: Cell culture, cell counting, ELISA assay, TUNEL, flow cymetry, Wester...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Li, Hong-Liang, Chen, Dan-Dan, Li, Xiao-Hong, Zhang, Hai-Wei, Lü, Jun-Hua, Ren, Xian-Da, Wang, Cun-Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658354/
https://ncbi.nlm.nih.gov/pubmed/11925595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v8.i2.217
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