Inhibition of haematogenous metastasis of colon cancer in mice by a selective COX-2 inhibitor, JTE-522

It is proposed that non-steroidal anti-inflammatory drugs (NSAIDs) reduce colorectal tumorigenesis by inhibition of cyclooxygenase (COX). COX is a key enzyme in the conversion of arachidonic acid to prostaglandins and two isoforms of COX have been characterized, COX-1 and COX-2. Multiple studies hav...

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Detalhes bibliográficos
Main Authors: Tomozawa, S, Nagawa, H, Tsuno, N, Hatano, K, Osada, T, Kitayama, J, Sunami, E, Nita, M E, Ishihara, S, Yano, H, Tsuruo, T, Shibata, Y, Muto, T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362975/
https://ncbi.nlm.nih.gov/pubmed/10604722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6694262
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