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JTE-522, a selective COX-2 inhibitor, inhibits growth of pulmonary metastases of colorectal cancer in rats

BACKGROUND: Epidemiological studies have shown that individuals who regularly consume NSAIDs have lower rates of mortality associated with colorectal cancer. Because COX-2 inhibitors prevent tumor growth through some mechanisms, we assessed the effect of JTE-522, a selective COX-2 inhibitor, on pulm...

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Detalhes bibliográficos
Main Authors: Kobayashi, Hirotoshi, Uetake, Hiroyuki, Higuchi, Tetsuro, Enomoto, Masayuki, Sugihara, Kenichi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC555553/
https://ncbi.nlm.nih.gov/pubmed/15743541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-5-26
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