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Changes of NF-κB, p53, Bcl-2 and caspase in apoptosis induced by JTE-522 in human gastric adenocarcinoma cell line AGS cells: role of reactive oxygen species
AIM: To identify whether JTE-522 can induce apoptosis in AGS cells and ROS also involved in the process, and to investigate the changes in NF-κB, p53, bcl-2 and caspase in the apoptosis process. METHODS: Cell culture, MTT, Electromicroscopy, agarose gel electrophoresis, lucigenin, Western blot and e...
Shranjeno v:
izdano v: | World J Gastroenterol |
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Main Authors: | , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Baishideng Publishing Group Inc
2002
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4656415/ https://ncbi.nlm.nih.gov/pubmed/12046064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v8.i3.431 |
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