Changes of NF-κB, p53, Bcl-2 and caspase in apoptosis induced by JTE-522 in human gastric adenocarcinoma cell line AGS cells: role of reactive oxygen species

AIM: To identify whether JTE-522 can induce apoptosis in AGS cells and ROS also involved in the process, and to investigate the changes in NF-κB, p53, bcl-2 and caspase in the apoptosis process. METHODS: Cell culture, MTT, Electromicroscopy, agarose gel electrophoresis, lucigenin, Western blot and e...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Li, Hong-Liang, Chen, Dan-Dan, Li, Xiao-Hong, Zhang, Hai-Wei, Lü, Yan-Qing, Ye, Chun-Ling, Ren, Xian-Da
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2002
Assuntos:
Gastric Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656415/
https://ncbi.nlm.nih.gov/pubmed/12046064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v8.i3.431
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