Langerhans cells from women with cervical precancerous lesions become functionally responsive against human papillomavirus after activation with stabilized Poly-I:C

Human papillomavirus (HPV)-mediated suppression of Langerhans cell (LC) function can lead to persistent infection and development of cervical intraepithelial neoplasia (CIN). Women with HPV-induced high-grade CIN2/3 have not mounted an effective immune response against HPV, yet it is unknown if LC-m...

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Vydáno v:Clin Immunol
Hlavní autoři: DA SILVA, Diane M., WOODHAM, Andrew W., SKEATE, Joseph G., RIJKEE, Laurie K., TAYLOR, Julia R., BRAND, Heike E., MUDERSPACH, Laila I., ROMAN, Lynda D., YESSAIAN, Annie A., PHAM, Huyen Q., MATSUO, Koji, LIN, Yvonne G., McKEE, Greg M., SALAZAR, Andres M., KAST, W. Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658296/
https://ncbi.nlm.nih.gov/pubmed/26360252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2015.09.003
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