T cell ignorance is bliss: T cells are not tolerized by Langerhans cells presenting human papillomavirus antigens in the absence of costimulation

Human papillomavirus type 16 (HPV16) infections are intra-epithelial, and thus, HPV16 is known to interact with Langerhans cells (LCs), the resident epithelial antigen-presenting cells (APCs). The current paradigm for APC-mediated induction of T cell anergy is through delivery of T cell receptor sig...

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Detalhes bibliográficos
Publicado no:Papillomavirus Res
Main Authors: Woodham, Andrew W., Yan, Lisa, Skeate, Joseph G., van der Veen, Daniel, Brand, Heike E., Wong, Michael K., Da Silva, Diane M., Kast, W. Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862606/
https://ncbi.nlm.nih.gov/pubmed/27182559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pvr.2016.01.002
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