Langerhans cells from women with cervical precancerous lesions become functionally responsive against human papillomavirus after activation with stabilized Poly-I:C

Human papillomavirus (HPV)-mediated suppression of Langerhans cell (LC) function can lead to persistent infection and development of cervical intraepithelial neoplasia (CIN). Women with HPV-induced high-grade CIN2/3 have not mounted an effective immune response against HPV, yet it is unknown if LC-m...

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Publicado no:Clin Immunol
Main Authors: DA SILVA, Diane M., WOODHAM, Andrew W., SKEATE, Joseph G., RIJKEE, Laurie K., TAYLOR, Julia R., BRAND, Heike E., MUDERSPACH, Laila I., ROMAN, Lynda D., YESSAIAN, Annie A., PHAM, Huyen Q., MATSUO, Koji, LIN, Yvonne G., McKEE, Greg M., SALAZAR, Andres M., KAST, W. Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658296/
https://ncbi.nlm.nih.gov/pubmed/26360252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2015.09.003
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