FAM150A and FAM150B are activating ligands for anaplastic lymphoma kinase

Aberrant activation of anaplastic lymphoma kinase (ALK) has been described in a range of human cancers, including non-small cell lung cancer and neuroblastoma (Hallberg and Palmer, 2013). Vertebrate ALK has been considered to be an orphan receptor and the identity of the ALK ligand(s) is a critical...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Guan, Jikui, Umapathy, Ganesh, Yamazaki, Yasuo, Wolfstetter, Georg, Mendoza, Patricia, Pfeifer, Kathrin, Mohammed, Ateequrrahman, Hugosson, Fredrik, Zhang, Hongbing, Hsu, Amy W, Halenbeck, Robert, Hallberg, Bengt, Palmer, Ruth H
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658194/
https://ncbi.nlm.nih.gov/pubmed/26418745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.09811
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