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Influence of glucosamine on the bioactivity of insulin delivered subcutaneously and in an oral nanodelivery system

The aim of the work reported herein was to study the effect of glucosamine HCl (GlcN·HCl) on the bioactivity (BA) of insulin, administered via subcutaneous (SC) and oral routes, in adult male Sprague Dawley rats. The oral insulin delivery system (insulin–chitosan reverse micelle [IC-RM]) was prepare...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Al-Kurdi, Zakieh I, Chowdhry, Babur Z, Leharne, Stephen A, Qinna, Nidal A, Al Omari, Mahmoud MH, Badwan, Adnan A
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657806/
https://ncbi.nlm.nih.gov/pubmed/26640369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S91974
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