ABCC8 R1420H Loss-of-Function Variant in a Southwest American Indian Community: Association With Increased Birth Weight and Doubled Risk of Type 2 Diabetes

Missense variants in KCNJ11 and ABCC8, which encode the KIR6.2 and SUR1 subunits of the β-cell K(ATP) channel, have previously been implicated in type 2 diabetes, neonatal diabetes, and hyperinsulinemic hypoglycemia of infancy (HHI). To determine whether variation in these genes affects risk for typ...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Diabetes
Κύριοι συγγραφείς: Baier, Leslie J., Muller, Yunhua Li, Remedi, Maria Sara, Traurig, Michael, Piaggi, Paolo, Wiessner, Gregory, Huang, Ke, Stacy, Alyssa, Kobes, Sayuko, Krakoff, Jonathan, Bennett, Peter H., Nelson, Robert G., Knowler, William C., Hanson, Robert L., Nichols, Colin G., Bogardus, Clifton
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Diabetes Association 2015
Θέματα:
Genetics/Genomes/Proteomics/Metabolomics
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657583/
https://ncbi.nlm.nih.gov/pubmed/26246406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-0459
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

Παρόμοια τεκμήρια