Assessing FOXO1A as a Potential Susceptibility Locus for Type 2 Diabetes and Obesity in American Indians

OBJECTIVE: A prior genome-wide association study (GWAS) in Pima Indians identified variation within FOXO1A that modestly associated with early-onset (onset age<25years) type 2 diabetes (T2D). FOXO1A encodes the forkhead transcription factor involved in pancreatic β-cell growth and hypothalamic en...

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Publicat a:Obesity (Silver Spring)
Autors principals: Muller, Yunhua L., Hanson, Robert L., Wiessner, Gregory, Nieboer, Lori, Kobes, Sayuko, Piaggi, Paolo, AbdusSamad, Mahdi, Okani, Chidinma, Knowler, William C., Bogardus, Clifton, Baier, Leslie J.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586407/
https://ncbi.nlm.nih.gov/pubmed/26337673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.21236
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