Assessing the Role of 98 Established Loci for Body Mass Index in American Indians

OBJECTIVE: Meta-analyses of genome-wide association studies (GWAS) in Europeans have identified >98 loci for Body Mass Index (BMI). We analyze transferability of these established associations in Pima Indians. METHODS: Among 98 lead SNPs, 82 had minor allele frequency≥0.01 in Pima Indians, and we...

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Detalhes bibliográficos
Publicado no:Obesity (Silver Spring)
Main Authors: Muller, Yunhua L., Hanson, Robert L., Piaggi, Paolo, Chen, Peng, Wiessner, Gregory, Okani, Chidinma, Skelton, Graham, Kobes, Sayuko, Hsueh, Wen-Chi, Knowler, William C., Bogardus, Clifton, Baier, Leslie J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478540/
https://ncbi.nlm.nih.gov/pubmed/30887699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.22433
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