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A pH-Responsive MRI Agent that Can Be Activated Beyond the Tissue MT Window()

A terbium-based complex that displays a water exchange CEST resonance well-outside the normal magnetization transfer (MT) frequency range of tissues provides a direct readout of pH by MRI. Deprotonation of the phenolic proton in this complex results in a frequency shift of 56 ppm in a bound water mo...

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Publicat a:Angew Chem Int Ed Engl
Autors principals: Wang, Xiaojing, Wu, Yunkou, Soesbe, Todd C., Yu, Jing, Zhao, Piyu, Kiefer, Garry E., Sherry, A. Dean
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657548/
https://ncbi.nlm.nih.gov/pubmed/26096197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201502497
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