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Combining CRISPR/Cas9 and rAAV Templates for Efficient Gene Editing
Altering endogenous genes in cells is an integral tool of modern cell biology. The ease-of-use of the CRISPR/Cas9 system to introduce genomic DNA breaks at specific sites in vivo has led to its rapid and wide adoption. In the absence of a DNA template, the lesion is repaired by nonhomologous end joi...
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| 發表在: | Nucleic Acid Ther |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Mary Ann Liebert, Inc.
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4657517/ https://ncbi.nlm.nih.gov/pubmed/26540648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2015.0545 |
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