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Combining CRISPR/Cas9 and rAAV Templates for Efficient Gene Editing

Altering endogenous genes in cells is an integral tool of modern cell biology. The ease-of-use of the CRISPR/Cas9 system to introduce genomic DNA breaks at specific sites in vivo has led to its rapid and wide adoption. In the absence of a DNA template, the lesion is repaired by nonhomologous end joi...

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Bibliografski detalji
Izdano u:Nucleic Acid Ther
Glavni autori: Kaulich, Manuel, Dowdy, Steven F.
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657517/
https://ncbi.nlm.nih.gov/pubmed/26540648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2015.0545
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