Impaired uptake of conjugated bile acids and hepatitis b virus pres1-binding in na(+)-taurocholate cotransporting polypeptide knockout mice

The Na(+)-taurocholate cotransporting polypeptide (NTCP) mediates uptake of conjugated bile acids (BAs) and is localized at the basolateral membrane of hepatocytes. It has recently been recognized as the receptor mediating hepatocyte-specific entry of hepatitis B virus and hepatitis delta virus. Myr...

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Detalles Bibliográficos
Publicado en:Hepatology
Main Authors: Slijepcevic, Davor, Kaufman, Christina, Wichers, Catharina GK, Gilglioni, Eduardo H, Lempp, Florian A, Duijst, Suzanne, de Waart, Dirk R, Oude Elferink, Ronald PJ, Mier, Walter, Stieger, Bruno, Beuers, Ulrich, Urban, Stephan, van de Graaf, Stan FJ
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley & Sons, Ltd 2015
Assuntos:
Autoimmune, Cholestatic and Biliary Disease
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657468/
https://ncbi.nlm.nih.gov/pubmed/25641256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27694
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