Role of Nucleosomal Occupancy in the Epigenetic Silencing of the MLH1 CpG Island

Epigenetic silencing of tumor suppressor genes is generally thought to involve DNA cytosine methylation, covalent modifications of histones, and chromatin compaction. Here, we show that silencing of the three transcription start sites in the bidirectional MLH1 promoter CpG island in cancer cells inv...

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Detaylı Bibliyografya
Yayımlandı:Cancer Cell
Asıl Yazarlar: Lin, Joy C., Jeong, Shinwu, Liang, Gangning, Takai, Daiya, Fatemi, Merhnaz, Tsai, Yvonne C., Egger, Gerda, Gal-Yam, Einav Nili, Jones, Peter A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657456/
https://ncbi.nlm.nih.gov/pubmed/17996647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2007.10.014
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