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Molecular interplay between T-Antigen and splicing factor, arginine/serine-rich 1 (SRSF1) controls JC virus gene expression in glial cells

BACKGROUND: Human polyomavirus JCV is the etiologic agent of progressive multifocal leukoencephalopathy (PML), a fatal demyelinating disease characterized by lytic infection of glial cells in the central nervous system. PML is seen primarily in immunosuppressed patients and is mainly classified as a...

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Publicat a:Virol J
Autors principals: Craigie, Michael, Regan, Patrick, Otalora, Yolanda-Lopez, Sariyer, Ilker Kudret
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657255/
https://ncbi.nlm.nih.gov/pubmed/26596376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-015-0426-x
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