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Loss of Polo ameliorates APP-induced Alzheimer’s disease-like symptoms in Drosophila
The amyloid precursor protein (APP) has been implicated in the pathogenesis of Alzheimer’s disease (AD). Despite extensive studies, little is known about the regulation of APP’s functions in vivo. Here we report that expression of human APP in Drosophila, in the same temporal-spatial pattern as its...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4657023/ https://ncbi.nlm.nih.gov/pubmed/26597721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16816 |
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