Knockdown of EMMPRIN improves adverse remodeling mediated by IL-18 in the post-infarcted heart

Interleukin-18 (IL-18) exacerbates cardiac dysfunction following myocardial infarction (MI). Extracellular matrix metalloproteinase inducer (EMMPRIN) has been shown to exacerbate ventricular remodeling via induction of extracellular matrix metalloproteinase (MMP) synthesis. While up-regulation of EM...

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Publicat a:Am J Transl Res
Autors principals: Su, Zizhuo, Lin, Rongjie, Chen, Yuyang, Shu, Xiaorong, Zhang, Haifeng, Nie, Ruqiong, Wang, Jingfeng, Xie, Shuanglun
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656767/
https://ncbi.nlm.nih.gov/pubmed/26692934
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