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Oxidized low-density lipoprotein inhibits the degradation of cyclophilin A via the lysosome in vascular smooth muscle cells

Background: Cyclophilin A (CyPA) plays an important role in the progression of atherosclerosis. Additionally, it has been reported that lysosomal function is markedly impaired in atherosclerosis induced by oxidized low-density lipoprotein (ox-LDL). As the CyPA degradation pathway remains to be eluci...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Su, Zizhuo, Lin, Maohuan, Su, Yinqing, Li, Jiajie, Lin, Rongjie, Wu, Maoxiong, Wang, Xiaoyu, Huang, Lili, Chen, Yuyang, Shu, Xiaorong, Liang, Shumin, Zhang, Haifeng, Huang, Tucheng, Nie, Ruqiong, Wang, Jingfeng, Xie, Shuanglun
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407676/
https://ncbi.nlm.nih.gov/pubmed/32774749
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