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Potential inhibition of cytochrome P450 3A4 by propofol in human primary hepatocytes
AIM: Hepatic cytochrome P450 isoenzymes constitute a superfamily of hemoproteins that play a major role in the metabolism of endogenous compounds and in the detoxification of xenobiotic molecules. P450 3A4 is one of the most important forms in human being, and mediates the metabolism of around 70% o...
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| Pubblicato in: | World J Gastroenterol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Baishideng Publishing Group Inc
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4656652/ https://ncbi.nlm.nih.gov/pubmed/12970884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v9.i9.1959 |
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