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Effects of histone acetylation and DNA methylation on p21(WAF1) regulation

Cell cycle progression is regulated by interactions between cyclins and c yclin-dependent kinases (CDKs). p21(WAF1) is one of the CIP/KIP family which inhib its CDKs activity. Increased expression of p21(WAF1) may play an important role in the growth arrest induced in transformed cells. Although the...

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Publicat a:World J Gastroenterol
Autors principals: Fang, Jing-Yuan, Lu, You-Yong
Format: Artigo
Idioma:Inglês
Publicat: Baishideng Publishing Group Inc 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656409/
https://ncbi.nlm.nih.gov/pubmed/12046058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v8.i3.400
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