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Establishment of a simple assay in vitro for hepatitis C virus NS3 serine protease based on recombinant substrate and single-chain protease

AIM: To establish a simple and convenient assay in vitro for the Hepatitis C virus NS3 serine protease based on the recombinant protease and substrate, and to evaluate its feasibility in screening the enzyme inhibitors. METHODS: Based on the crystallographic structure of hepatitis C virus (HCV) seri...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Du, Gui-Xin, Hou, Li-Hua, Guan, Rong-Bin, Tong, Yi-Gang, Wang, Hai-Tao
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656386/
https://ncbi.nlm.nih.gov/pubmed/12439931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v8.i6.1088
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