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Establishment of a cell-based assay system for hepatitis C virus serine protease and its primary applications

AIM: To establish an efficient, sensitive, cell-based assay system for NS3 serine protease in an effort to study further the property of hepatitis C virus (HCV) and develop new antiviral agents. METHODS: We constructed pCI-neo-NS3/4A-SEAP chimeric plasmid, in which the secreted alkaline phosphatase...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Mao, Hong-Xia, Lan, Shui-Yun, Hu, Yun-Wen, Xiang, Li, Yuan, Zheng-Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4656523/
https://ncbi.nlm.nih.gov/pubmed/14606079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v9.i11.2474
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