Molecular mechanism of substrate specificity for delta 6 desaturase from Mortierella alpina and Micromonas pusilla

The ω6 and ω3 pathways are two major pathways in the biosynthesis of PUFAs. In both of these, delta 6 desaturase (FADS6) is a key bifunctional enzyme desaturating linoleic acid or α-linolenic acid. Microbial species have different propensity for accumulating ω6- or ω3-series PUFAs, which may be dete...

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Udgivet i:J Lipid Res
Main Authors: Shi (史海粟), Haisu, Chen (陈海琴), Haiqin, Gu (顾震南), Zhennan, Song (宋元达), Yuanda, Zhang (张灏), Hao, Chen (陈卫), Wei, Chen (陈永泉), Yong Q.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2015
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655987/
https://ncbi.nlm.nih.gov/pubmed/26486975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M062158
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