Diaphragm dysfunction in heart failure is accompanied by increases in neutral sphingomyelinase activity and ceramide content

AIMS: Chronic heart failure (CHF) causes inspiratory (diaphragm) muscle weakness and fatigue that contributes to dyspnoea and limited physical capacity in patients. However, the mechanisms that lead to diaphragm dysfunction in CHF remain poorly understood. Cytokines and angiotensin II are elevated i...

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Détails bibliographiques
Publié dans:Eur J Heart Fail
Auteurs principaux: Empinado, Hyacinth M., Deevska, Gergana M., Nikolova-Karakashian, Mariana, Yoo, Jeung-Ki, Christou, Demetra D., Ferreira, Leonardo F.
Format: Artigo
Langue:Inglês
Publié: 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655596/
https://ncbi.nlm.nih.gov/pubmed/24596158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejhf.73
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