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Enteral siRNA delivery technique for therapeutic gene silencing in the liver via the lymphatic route
An efficient targeting delivery technology is needed for functional oligonucleotides to exert their potential effect on the target gene without an adverse effect in vivo. Development of enteral delivery systems for nucleic acids is a major challenge because of their large molecular size and instabil...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4655470/ https://ncbi.nlm.nih.gov/pubmed/26593819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17035 |
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