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Intrahaplotypic Variants Differentiate Complex Linkage Disequilibrium within Human MHC Haplotypes

Distinct regions of long-range genetic fixation in the human MHC region, known as conserved extended haplotypes (CEHs), possess unique genomic characteristics and are strongly associated with numerous diseases. While CEHs appear to be homogeneous by SNP analysis, the nature of fine variations within...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Lam, Tze Hau, Tay, Matthew Zirui, Wang, Bei, Xiao, Ziwei, Ren, Ee Chee
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655331/
https://ncbi.nlm.nih.gov/pubmed/26593880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16972
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