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Intrahaplotypic Variants Differentiate Complex Linkage Disequilibrium within Human MHC Haplotypes

Distinct regions of long-range genetic fixation in the human MHC region, known as conserved extended haplotypes (CEHs), possess unique genomic characteristics and are strongly associated with numerous diseases. While CEHs appear to be homogeneous by SNP analysis, the nature of fine variations within...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Lam, Tze Hau, Tay, Matthew Zirui, Wang, Bei, Xiao, Ziwei, Ren, Ee Chee
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655331/
https://ncbi.nlm.nih.gov/pubmed/26593880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16972
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