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Intrahaplotypic Variants Differentiate Complex Linkage Disequilibrium within Human MHC Haplotypes

Distinct regions of long-range genetic fixation in the human MHC region, known as conserved extended haplotypes (CEHs), possess unique genomic characteristics and are strongly associated with numerous diseases. While CEHs appear to be homogeneous by SNP analysis, the nature of fine variations within...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lam, Tze Hau, Tay, Matthew Zirui, Wang, Bei, Xiao, Ziwei, Ren, Ee Chee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655331/
https://ncbi.nlm.nih.gov/pubmed/26593880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16972
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