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FoCo: a simple and robust quantification algorithm of nuclear foci

BACKGROUND: The number of γH2AX foci per nucleus is an accepted measure of the number of DNA double-strand breaks in single cells. One of the experimental techniques for γH2AX detection in cultured cells is immunofluorescent labelling of γH2AX and nuclei followed by microscopy imaging and analysis....

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Lapytsko, Anastasiya, Kollarovic, Gabriel, Ivanova, Lyubomira, Studencka, Maja, Schaber, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654864/
https://ncbi.nlm.nih.gov/pubmed/26589438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0816-5
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