Neurological disease induced in transgenic mice expressing the env gene of the Cas-Br-E murine retrovirus.
The Cas-Br-E murine leukemia virus induces a spongiform myeloencephalopathy in susceptible mice. We constructed transgenic mice harboring either the viral genome (in a replication-defective form) or only its env gene. Low levels of expression of either transgene resulted in mild neuropathology and/o...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1993
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46547/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8389454/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.10.4538 |
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