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MVP-Associated Filamin A Mutations Affect FlnA-PTPN12 (PTP-PEST) Interactions

Although the genetic basis of mitral valve prolapse (MVP) has now been clearly established, the molecular and cellular mechanisms involved in the pathological processes associated to a specific mutation often remain to be determined. The FLNA gene (encoding Filamin A; FlnA) was the first gene associ...

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Podrobná bibliografie
Vydáno v:J Cardiovasc Dev Dis
Hlavní autoři: Duval, Damien, Labbé, Pauline, Bureau, Léa, Le Tourneau, Thierry, Norris, Russell A., Markwald, Roger R., Levine, Robert, Schott, Jean-Jacques, Mérot, Jean
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654411/
https://ncbi.nlm.nih.gov/pubmed/26594644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcdd2030233
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