Valvular dystrophy associated filamin A mutations reveal a new role of its first repeats in small-GTPase regulation

Filamin A (FlnA) is a ubiquitous actin binding protein which anchors various transmembrane proteins to the cell cytoskeleton and provides a scaffold to many cytoplasmic signaling proteins involved in actin cytoskeleton remodeling in response to mechanical stress and cytokines stimulation. Although t...

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Main Authors: Duval, D., Lardeux, A., Le Tourneau, T., Norris, R.A., Markwald, R.R., Sauzeau, V., Probst, V., Le Marec, H., Levine, R., Schott, J.J., Merot, J.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928473/
https://ncbi.nlm.nih.gov/pubmed/24200678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2013.10.022
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