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Valvular dystrophy associated filamin A mutations reveal a new role of its first repeats in small-GTPase regulation
Filamin A (FlnA) is a ubiquitous actin binding protein which anchors various transmembrane proteins to the cell cytoskeleton and provides a scaffold to many cytoplasmic signaling proteins involved in actin cytoskeleton remodeling in response to mechanical stress and cytokines stimulation. Although t...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3928473/ https://ncbi.nlm.nih.gov/pubmed/24200678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2013.10.022 |
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