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Systemic immunological effects of cytokine genes injected into skeletal muscle.

Somatic gene therapy is an interesting approach for the delivery of cytokines for prolonged periods. The present experiments show that direct injections into mouse skeletal muscle of cDNA expression vectors encoding interleukin 2 (IL-2), IL-4, or type beta 1 transforming growth factor (TGF-beta 1) i...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Raz, E, Watanabe, A, Baird, S M, Eisenberg, R A, Parr, T B, Lotz, M, Kipps, T J, Carson, D A
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1993
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46544/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8506293/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.10.4523
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