Systemic immunological effects of cytokine genes injected into skeletal muscle.

Somatic gene therapy is an interesting approach for the delivery of cytokines for prolonged periods. The present experiments show that direct injections into mouse skeletal muscle of cDNA expression vectors encoding interleukin 2 (IL-2), IL-4, or type beta 1 transforming growth factor (TGF-beta 1) i...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Raz, E, Watanabe, A, Baird, S M, Eisenberg, R A, Parr, T B, Lotz, M, Kipps, T J, Carson, D A
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1993
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46544/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8506293/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.10.4523
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