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In vivo acceleration of heart relaxation performance by parvalbumin gene delivery

Defective cardiac muscle relaxation plays a causal role in heart failure. Shown here is the new in vivo application of parvalbumin, a calcium-binding protein that facilitates ultrafast relaxation of specialized skeletal muscles. Parvalbumin is not naturally expressed in the heart. We show that parva...

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Detalhes bibliográficos
Main Authors: Szatkowski, Michael L., Westfall, Margaret V., Gomez, Carlen A., Wahr, Philip A., Michele, Daniel E., DelloRusso, Christiana, Turner, Immanuel I., Hong, Katie E., Albayya, Faris P., Metzger, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC198873/
https://ncbi.nlm.nih.gov/pubmed/11160135
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