In vivo acceleration of heart relaxation performance by parvalbumin gene delivery

Defective cardiac muscle relaxation plays a causal role in heart failure. Shown here is the new in vivo application of parvalbumin, a calcium-binding protein that facilitates ultrafast relaxation of specialized skeletal muscles. Parvalbumin is not naturally expressed in the heart. We show that parva...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Szatkowski, Michael L., Westfall, Margaret V., Gomez, Carlen A., Wahr, Philip A., Michele, Daniel E., DelloRusso, Christiana, Turner, Immanuel I., Hong, Katie E., Albayya, Faris P., Metzger, Joseph M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC198873/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160135/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI9862
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