WDR82 Negatively Regulates Cellular Antiviral Response by Mediating TRAF3 Polyubiquitination in Multiple Cell Lines

Upon virus infection, retinoic acid–inducible gene I–like receptors in host cells recognize viral RNA and activate type I IFN expression. Previously, we identified WD repeat domain (WDR) 5 as one positive regulator for pathway activation. In this study, we report that WDR82, a homolog protein of WDR...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Immunol
Egile Nagusiak: Zhu, Kun, Wang, Xiang, Ju, Lin-Gao, Zhu, Yuan, Yao, Jie, Wang, Yanyi, Wu, Min, Li, Lian-Yun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: AAI 2015
Gaiak:
Innate Immunity and Inflammation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654227/
https://ncbi.nlm.nih.gov/pubmed/26519536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500339
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