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WDR82 Negatively Regulates Cellular Antiviral Response by Mediating TRAF3 Polyubiquitination in Multiple Cell Lines

Upon virus infection, retinoic acid–inducible gene I–like receptors in host cells recognize viral RNA and activate type I IFN expression. Previously, we identified WD repeat domain (WDR) 5 as one positive regulator for pathway activation. In this study, we report that WDR82, a homolog protein of WDR...

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Bibliografische gegevens
Gepubliceerd in:J Immunol
Hoofdauteurs: Zhu, Kun, Wang, Xiang, Ju, Lin-Gao, Zhu, Yuan, Yao, Jie, Wang, Yanyi, Wu, Min, Li, Lian-Yun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: AAI 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654227/
https://ncbi.nlm.nih.gov/pubmed/26519536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500339
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