WDR82 Negatively Regulates Cellular Antiviral Response by Mediating TRAF3 Polyubiquitination in Multiple Cell Lines

Upon virus infection, retinoic acid–inducible gene I–like receptors in host cells recognize viral RNA and activate type I IFN expression. Previously, we identified WD repeat domain (WDR) 5 as one positive regulator for pathway activation. In this study, we report that WDR82, a homolog protein of WDR...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Zhu, Kun, Wang, Xiang, Ju, Lin-Gao, Zhu, Yuan, Yao, Jie, Wang, Yanyi, Wu, Min, Li, Lian-Yun
Format: Artigo
Langue:Inglês
Publié: AAI 2015
Sujets:
Innate Immunity and Inflammation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654227/
https://ncbi.nlm.nih.gov/pubmed/26519536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500339
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