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WDR82 Negatively Regulates Cellular Antiviral Response by Mediating TRAF3 Polyubiquitination in Multiple Cell Lines

Upon virus infection, retinoic acid–inducible gene I–like receptors in host cells recognize viral RNA and activate type I IFN expression. Previously, we identified WD repeat domain (WDR) 5 as one positive regulator for pathway activation. In this study, we report that WDR82, a homolog protein of WDR...

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Podrobná bibliografie
Vydáno v:J Immunol
Hlavní autoři: Zhu, Kun, Wang, Xiang, Ju, Lin-Gao, Zhu, Yuan, Yao, Jie, Wang, Yanyi, Wu, Min, Li, Lian-Yun
Médium: Artigo
Jazyk:Inglês
Vydáno: AAI 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654227/
https://ncbi.nlm.nih.gov/pubmed/26519536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500339
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