WDR82 Negatively Regulates Cellular Antiviral Response by Mediating TRAF3 Polyubiquitination in Multiple Cell Lines

Upon virus infection, retinoic acid–inducible gene I–like receptors in host cells recognize viral RNA and activate type I IFN expression. Previously, we identified WD repeat domain (WDR) 5 as one positive regulator for pathway activation. In this study, we report that WDR82, a homolog protein of WDR...

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Bibliografske podrobnosti
izdano v:J Immunol
Main Authors: Zhu, Kun, Wang, Xiang, Ju, Lin-Gao, Zhu, Yuan, Yao, Jie, Wang, Yanyi, Wu, Min, Li, Lian-Yun
Format: Artigo
Jezik:Inglês
Izdano: AAI 2015
Teme:
Innate Immunity and Inflammation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654227/
https://ncbi.nlm.nih.gov/pubmed/26519536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500339
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