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Tripartite Motif (TRIM) 12c, a Mouse Homolog of TRIM5, Is a Ubiquitin Ligase That Stimulates Type I IFN and NF-κB Pathways along with TNFR-Associated Factor 6

Tripartite motif (TRIM) protein TRIM5 of the primate species restricts replication of HIV and other retroviruses. Whereas primates have a single TRIM5 gene, the corresponding locus in the mouse has expanded during evolution, now containing more than eight related genes. Owing to the complexity of th...

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Pubblicato in:J Immunol
Autori principali: Chang, Tsung-Hsien, Yoshimi, Ryusuke, Ozato, Keiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: AAI 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654225/
https://ncbi.nlm.nih.gov/pubmed/26503954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402064
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