Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies

Histone deacetylase (HDAC) inhibitors (HDACis) have demonstrated activity in hematological and solid malignancies. Vorinostat, romidepsin, belinostat, and panobinostat are Food and Drug Administration–approved for hematological malignancies and inhibit class II and/or class I HDACs, including HDAC1,...

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Foilsithe in:Blood
Main Authors: Matthews, Geoffrey M., Mehdipour, Parinaz, Cluse, Leonie A., Falkenberg, Katrina J., Wang, Eric, Roth, Mareike, Santoro, Fabio, Vidacs, Eva, Stanley, Kym, House, Colin M., Rusche, James R., Vakoc, Christopher R., Zuber, Johannes, Minucci, Saverio, Johnstone, Ricky W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Hematology 2015
Ábhair:
Lymphoid Neoplasia
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653767/
https://ncbi.nlm.nih.gov/pubmed/26447190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-03-632984
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