Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies

Histone deacetylase (HDAC) inhibitors (HDACis) have demonstrated activity in hematological and solid malignancies. Vorinostat, romidepsin, belinostat, and panobinostat are Food and Drug Administration–approved for hematological malignancies and inhibit class II and/or class I HDACs, including HDAC1,...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Matthews, Geoffrey M., Mehdipour, Parinaz, Cluse, Leonie A., Falkenberg, Katrina J., Wang, Eric, Roth, Mareike, Santoro, Fabio, Vidacs, Eva, Stanley, Kym, House, Colin M., Rusche, James R., Vakoc, Christopher R., Zuber, Johannes, Minucci, Saverio, Johnstone, Ricky W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653767/
https://ncbi.nlm.nih.gov/pubmed/26447190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-03-632984
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