ATF4 plays a pivotal role in the development of functional hematopoietic stem cells in mouse fetal liver

The fetal liver (FL) serves as a predominant site for expansion of functional hematopoietic stem cells (HSCs) during mouse embryogenesis. However, the mechanisms for HSC development in FL remain poorly understood. In this study, we demonstrate that deletion of activating transcription factor 4 (ATF4...

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Vydáno v:Blood
Hlavní autoři: Zhao, Yunze, Zhou, Jie, Liu, Dan, Dong, Fang, Cheng, Hui, Wang, Weili, Pang, Yakun, Wang, Yajie, Mu, Xiaohuan, Ni, Yanli, Li, Zhuan, Xu, Huiyu, Hao, Sha, Wang, Xiaochen, Ma, Shihui, Wang, Qian-fei, Xiao, Guozhi, Yuan, Weiping, Liu, Bing, Cheng, Tao
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2015
Témata:
Hematopoiesis and Stem Cells
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653766/
https://ncbi.nlm.nih.gov/pubmed/26384355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-03-633354
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