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Notch1-induced T cell leukemia can be potentiated by microenvironmental cues in the spleen

BACKGROUND: Leukemia is a systemic malignancy originated from hematopoietic cells. The extracellular environment has great impacts on the survival, proliferation and dissemination of leukemia cells. The spleen is an important organ for extramedullary hematopoiesis and a common infiltration site in l...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Ma, Shihui, Shi, Yingxu, Pang, Yakun, Dong, Fang, Cheng, Hui, Hao, Sha, Xu, Jing, Zhu, Xiaofan, Yuan, Weiping, Cheng, Tao, Zheng, Guoguang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229605/
https://ncbi.nlm.nih.gov/pubmed/25366136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-014-0071-7
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